Emerging insights into mesenchymal stem cells and exosome-based therapies for liver injury

Emerging insights into mesenchymal stem cells and exosome-based therapies for liver injury

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Hepatic ischemia-reperfusion injury, fatty liver, liver fibrosis, liver peroxidative injury, and drug-induced liver injury are among the most common liver diseases.Mesenchymal stem cells (MSCs) possess multi-lineage differentiation potential and immunomodulatory functions.In the treatment of liver injury, MSCs can promote repair through homing effects, direct differentiation into hepatocyte-like cells (HLCs), immunomodulation, and anti-fibrotic mechanisms.Clinically, MSCs blackmores ache relief focus review contribute to liver injury repair either directly or indirectly via the wella color touch 77 45 secretion of exosomes.

Beyond their reparative role, MSC-derived exosomes can also serve as molecular biomarkers for the diagnosis and prognosis of liver diseases [1].Establishing higher-quality standards, robust auditing and evaluation systems, and conducting deeper mechanistic studies are essential prerequisites for the future clinical application of MSCs in the treatment of liver diseases.